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Boto Genie®

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BOTULINUM TOXIN TYPE A

(PURIFIED NEUROTOXIN COMPLEX)

DESCRIPTION :

BOTO GENIE ® is a biologically active and highly purified preparation of Botulinum toxin Type A. This is an extremely potent neurotoxin complex which causes relaxation of muscles, marked reduction in gland secretory activity and silencing of nociceptor function on its absorption. The medical science has developed methodology to derive magical drug effect by unique formulation and controlled administration techniques. It has been used to correct undesirable muscular activity for a considerable period without surgical intervention. This action is reversible in nature in a few months. Since BOTO GENIE® is in a highly purified form & is used in minute quantities, it does not induce any immunological response even after several treatments in most subjects. BOTO GENIE® conforms to Ph.Eur.[/vc_column_text][/vc_column][vc_column width=”1/3″ el_class=”block2″][vc_single_image image=”3888″ img_size=”full” alignment=”center” el_class=”img”][/vc_column][/vc_row][vc_row el_class=”product-box” css=”.vc_custom_1512432424869{padding-top: 35px !important;}”][vc_column width=”1/3″ el_class=”block3″][vc_row_inner css=”.vc_custom_1512431727138{margin-top: 0px !important;margin-bottom: 0px !important;}”][vc_column_inner][vc_single_image image=”3346″ img_size=”24×24″ el_class=”img”][vc_column_text]COMPOSITION :

BOTO GENIE® 100 or 50 unit vial (Freeze dried )
Botulinum toxin Type A………….100 / 50 units
(Purified Neurotoxin Complex )
Lactose (Stabilizer ) ……………..5mg
Reconstitute with diluent provided
(Sodium chloride injection I.P., 0.9% W/V)

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Available in 50 &100 unit vial along with appropriate diluent.

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Safe and effective use of BOTO GENIE® depends on selection of correct dose and administration techniques. It is extremely important for physician to know the detailed muscular & other anatomical aspect of the area proposed to be treated, any alteration to the anatomy due to prior surgical procedure for good results and success.

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CONTRA- INDICATION :

Hypersensitivity to any ingredient in formulation.
Infection at the proposed site of inoculation.

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Localized weakness of the injection muscles represents the expected desirable action of the drug , however weakness of adjacent muscles may also occur due to spread of toxin

Skin rash , pruritus , allergic reaction , localized pain , bruising may be associated with the injection which may occur rarely.
Overdose : Excessive doses may cause distant and profound neuromuscular paralysis. There is no specification antidote. General supportive care is advised

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Store BOTO GENIE^® at 2⁰C to 8⁰C.
Shelf life of BOTO GENIE^® is 36 months.
BOTO GENIE^® reconstituted in aseptic conditions can be stored at 2⁰C to 8⁰C for 4 hrs.

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Bi Meningo™

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MENINGOCOCCAL POLYSACCHARIDE VACCINE
(Group A & C)

DESCRIPTION :

Meningococcal Polysaccharide vaccine is to be used to protect against cerebrospinal meningitis and other diseases caused by Neisseria meningitidis (Group A & C). Bi Meningo™ fulfills the requirements of Meningococcal Polysaccharide Vaccine as given in Indian Pharmacopoeia.The manufacturing facilities meets the requirements of cGMP guidelines of revised schedule ‘M’ of Drugs & Cosmetics Act of Government of India.

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Vaccination is recommended in regions of endemic infection, travelers to countries with epidemic meningococcal disease, household or institutional contacts, military recruits etc.

It is also recommended for subjects living in closed communities and close contacts of patients/carriers of Meningococcal Group A & C.[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][vc_column width=”1/3″ el_class=”block4″][vc_row_inner el_class=”product-border”][vc_column_inner][vc_single_image image=”3353″ img_size=”24×24″ el_class=”img”][vc_column_text]COMPOSITION

Each dose (0.5ml) of vaccine contains:
Purified Polysaccharide of Neisseria meningitidis
-Group A…………………………….50 µg.
-Group C…….………………………50 µg.
-Lactose I.P.( Stabilizer)…………….5 mg.
-Thiomerosal I.P.(Preservative)…0.05 mg.

Administer the vaccine(0.5 ml) by intramuscular or subcutaneous route.

Hypersensitivity to any of the vaccine component.
Ongoing acute or chronic illness like fever, severe infection, persistent diarrhoea, vomiting

Administration of single 0.5ml dose of Bi Meningo™ (Group A & C) elicits a significant bactericidal antibody response in about 100% of subjects. Immunity is conferred for three years.
The seroconversion rate of children vaccinated under the age of two years is lower for the serogroup C. However, the seroconversion rate for the sero-group A is acceptable in children from the age of 6 months onwards.

Reaction to vaccination generally consists of localized injection site reaction (pain, redness), transient hyperthermia, headache, vomiting in children etc.

Store between 2^oC to 8^oC in the refrigerator. Product is good to use for 24 months from the date of manufacture.

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1. One dose in glass vial with diluent and disposable syringe.
2. Ten dose in glass vial with diluent.

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