MENINGOCOCCAL POLYSACCHARIDE VACCINE
(Group A & C)
DESCRIPTION :
Meningococcal Polysaccharide vaccine is to be used to protect against cerebrospinal meningitis and other diseases caused by Neisseria meningitidis (Group A & C). Bi Meningo™ fulfills the requirements of Meningococcal Polysaccharide Vaccine as given in Indian Pharmacopoeia.The manufacturing facilities meets the requirements of cGMP guidelines of revised schedule ‘M’ of Drugs & Cosmetics Act of Government of India.
INDICATIONS
Vaccination is recommended in regions of endemic infection, travelers to countries with epidemic meningococcal disease, household or institutional contacts, military recruits etc.
It is also recommended for subjects living in closed communities and close contacts of patients/carriers of Meningococcal Group A & C.
COMPOSITION
Each dose (0.5ml) of vaccine contains:
Purified Polysaccharide of Neisseria meningitidis
-Group A…………………………….50 µg.
-Group C…….………………………50 µg.
-Lactose I.P.( Stabilizer)…………….5 mg.
-Thiomerosal I.P.(Preservative)…0.05 mg.
ROUTE OF ADMINISTRATION
Administer the vaccine(0.5 ml) by intramuscular or subcutaneous route.
CONTRA- INDICATION
Hypersensitivity to any of the vaccine component.
Ongoing acute or chronic illness like fever, severe infection, persistent diarrhoea, vomiting
DOSAGE
Administration of single 0.5ml dose of Bi Meningo™ (Group A & C) elicits a significant bactericidal antibody response in about 100% of subjects. Immunity is conferred for three years.
The seroconversion rate of children vaccinated under the age of two years is lower for the serogroup C. However, the seroconversion rate for the sero-group A is acceptable in children from the age of 6 months onwards.
SIDE EFFECTS
Reaction to vaccination generally consists of localized injection site reaction (pain, redness), transient hyperthermia, headache, vomiting in children etc.
STORAGE
Store between 2oC to 8oC in the refrigerator. Product is good to use for 24 months from the date of manufacture.
PRESENTATION
1. One dose in glass vial with diluent and disposable syringe.
2. Ten dose in glass vial with diluent.