Veterinary Products

7 Dec

Rabies Veterinary Vaccine I.P., Inactivated, Cell Culture

Inactivated (Cell Culture)
(Pre Exposure and Post Bite Use)
Rabies Vet™

DESCRIPTION :

Rabies is a fatal neurological disease of canines specially dogs, wolves, jackals, mongoose, etc. It is caused by Rabies virus.

The incubation period varies from a few days to several months (usually 5-40 days) depending on the amount of virus injected during bite and nearness to brain & major nerve trunks etc. The disease takes the toll of its prey in almost 100% cases usually within 5-10 days of appearance of clinical symptoms. Rabies is transmitted by bites of rabid dogs and other canines to all domesticated animals which in most cases results in deaths if not treated.

The animals affected with Rabies-called rabid animals become either very violent or dumb. They get excited at slight disturbance & bite wooden, stony objects and any animal including man.

Rabies Vet™ has been prepared by inactivating Rabies virus (Pitman Moore strain) grown in VERO cell culture, with ß-propiolactone. It is available in liquid form adjuvanted with aluminium hydroxide gel. It meets Standards for rabies vaccine as per Indian Pharmacopoeia

The manufacturing facilities meet the requirements of cGMP guidelines of revised schedule `M’ of Government of India.

VACCINATION SCHEDULE :

One ml dose of vaccine is recommended as an aid in preventing rabies in animals e.g. Dogs, Cattle, and Sheep & Goat above 3 months age, regardless of species, age and size of animals. Booster injection is indicated 1-3 years after primary immunization as long as exposed animals remains at risk. Annual booster dose is recommended in endemic areas.

PROPHYLACTIC/PRE EXPOSURE USE
—Single dose for animals of 3 months of age and above. In case vaccine is given at 3 months
age then boosters vaccination after 4 weeks is recommended in endemic areas.
POST-BITE THERAPY/POST EXPOSURE USE
—Five doses to be given regularly at days 0, 3, 7, 14 and 28. Sixth dose at day 90 is optional (‘0’ day being the day of first injection after the bite/exposure of animal).

ADMINISTRATION :

Shake well before use. Administer by intramuscular route.

PRESENTATION :

1 ml, 5 ml & 10 ml vials.

STORAGE :

Store protected from light in a refrigerator (+2⁰C to +8^oC). Do not freeze.

In: Sheep Vaccine Veterinary Products

7 Dec

Clostridium Perfringens Vaccine, Inactivated, I.P. (Type B, C & D)

Each doses(2 ml) contains : Inactivated bacterin of Clostridium Perfringens type B, C & D ≥109,
adjuvanted with Aluminium hydroxide gel.It confers protection against the following common disease:

Disease	C1.perfringens Type	Host Animal & Disease Caused
– Lamb Dysentry -Piglets diarrhoea	Type ‘B’	•Lambs & Piglets upto 10-12 days causes •Dysentry & deaths •Causes haemorrhagic diarrhoea
-Struck -Enterotoxaemia -Piglets enterotoxaemia	Type ‘C’	•Adult Sheep causes acute gastrits & enterititis, sudden death •Adult goats causes neurotoxaemia, convulsions & death •2-10 days old piglets
-Enterotoxaemia (Pulpy Kidney)	Type ‘D’	•Adult sheep & goats and young lambs & kids where dams were not vaccinated become victims of this disease causing acute neurotoxaemia resulting in convulsions & death.

Disease

C1.perfringens Type

Host Animal & Disease Caused

– Lamb Dysentry

-Piglets diarrhoea

Type ‘B’

•Lambs & Piglets upto 10-12 days causes

•Dysentry & deaths

•Causes haemorrhagic diarrhoea

-Struck

-Enterotoxaemia

-Piglets enterotoxaemia

Type ‘C’

•Adult Sheep causes acute gastrits & enterititis, sudden death

•Adult goats causes neurotoxaemia, convulsions & death

•2-10 days old piglets

-Enterotoxaemia

(Pulpy Kidney)

Type ‘D’

•Adult sheep & goats and young lambs & kids where dams were not vaccinated become victims of this disease causing acute neurotoxaemia resulting in convulsions & death.

POST VACCINATION REACTION:
Vaccinate animals with vaccine after shaking as subcutaneous injection. The dose for adult sheep, Goat & pigs is 2.0 ml and for young lamb, kid, piglets is 1.0 ml. Vaccine is normally given two times at 15 days intervals. Vaccine protects for 6-9 months.

Pregnant animals must be given vaccine two times at 15 days interval, atleast one months before parturition.
Lambs/kids/Piglets are protected for 4-6 weeks from vaccinated dams.
Lambs/kids/Piglets from unvaccinated dams should be vaccinated within one week of birth or soon after.

AVAILABILITY AND STORAGE
Vaccine is available in 50 dose(100 ml vial). It is stored at 2-8⁰C in cold store/refrigerator. Purchase vaccine from authorized chemist only. Consult veterinary doctors/specialists.

In: Sheep Vaccine Veterinary Products

7 Dec

Peste Des Petitis Ruminants Live, I.P.

DESCRIPTION :

PPR vaccine is an attenuated live viral vaccine(Sungri strain, developed by the I.V.R.I. India) produced by using vero cell line adapted PPR virus. The virus is propagated in vero cells mixed with stabilizer and freeze dried. It is available in 20 & 100 dose vial with vaccine diluent.

COMPOSITION

Each dose of reconstituted vaccine contains not less than 10²⁵ TCID₅₀ of PPR vaccine virus. In addition, the vaccine contains the following components as stabilizer.
• Lactalbumin hydrolysate 2.5% w/v
• Sucrose 5.0 w/v

SIDE EFFECTS:

No adverse reaction is encountered.

SCHEDULE OF VACCINATION:

Primary vaccination at the age 4-6 months confers protection for full life of the animals(Sheep & Goats).

DOSAGE AND ADMINISTRATION:

Reconstitute the freeze dried vaccine with chilled diluent. Administer subcutaneously to each animal (Sheep / Goats). Pregnant animals can also be vaccinated, without causing any disturbance to the animal.

PRECAUTION:

Vaccine should be used under the supervision of Veterinary Doctor.
Separate H/D needle should be used for each animal.
Vaccine should be reconstituted in cold vaccine diluent after all the arrangements for starting of vaccination is complete.
Use the reconstituted vaccine within 1 hour by keeping over chilled pack in a thermocol box.
Burn empty vials or dip in boiling water.

STORAGE:

The freeze dried vaccine should be transported in ice box packed with chilled pack observing strict cold-chain and stored in refrigerator. The vaccine keeps well without significant loss of titre at +2 to 8⁰C for 2 years.

In: Sheep Vaccine Veterinary Products

7 Dec

Sheep Pox Vaccine I.P.

FOR USE IN SHEEP

Sheep pox is amongst the most virulent of diseases in Sheep. It is highly contagious and spreads by direct contact. The virus is highly resistant. It gains entry by inhalation and direct contacts with infected animal.Young animals are more susceptible than adults. The incubation period is 2-7 days in fulminating form and 10-20 days in mild benign form.

The disease is recognised by fever which lasts for 1-2 days before eruptions appear on area of skin, which are not covered by wool/hair. The affected animals do not eat, have difficulty in breathing, stand separately from healthy animals with their heads down, may have salivation, lacrimation, bronchial coughs and diarrhoea. The disease course is of 3-6 weeks.
DESCRIPTION :

This vaccine contains, attenuated virus in freeze dried form. The vaccine confers solid protection against pox disease in sheep. The vaccine is available in 50 & 100 dose vial with vaccine diluent.

VACCINATION PROGRAMME :

All sheep and lambs above two months of age should be vaccinated atleast once a year. Lambs & Kids vaccinated at less than 6 months age should be revaccinated at 6 months of age to boost immunity.

ADMINISTRATION :

The vaccine is reconstituted thoroughly in the chilled vaccine diluent provided. Inject vaccine subcutaneously in the ear flap skin or any other suitable location. Local pox lesion of 1.5 to 2.0 cm in diameter may develop in 6-8 days without generalization. Reconstituted vaccine should be kept cool and used within 2 hours of its reconstitution.

PRESENTATION :

Vaccine should be used under the direction of Veterinary Doctor.
Vaccine should be reconstituted in cold vaccine diluent after all the arrangements for starting of vaccination is complete.
Vaccinate healthy animals only.
Burn empty vials or dip in boiling water.
Vaccine diluent can be stored at room temperature.

AVAILABILITY AND STORAGE :

Vaccine is available in 50 & 100 dose vial with vaccine diluent. The vaccine should be stored at 2⁰-8⁰C in refrigerator.

In: Sheep Vaccine Veterinary Products

7 Dec

Clostridium Perfringens Vaccine, Inactivated I.P. (Type D, Enterotoxaemia vaccine)

Enterotoxaemia disease is usually seen in animals of one to three months age, although it can affect them at any age. This disease is mostly observed in the months of May, June & July. The disease is more often observed when the animals graze in the fields of pea, barley and corn or they are given high grain ration with less volume of leafy material to graze. It can cause death in 10-20% animals. Any type of treatment cannot save the affected animals; therefore, it is necessary to vaccinate animals before the disease strikes them.
The flock of diseased animals should be given no feed for 2 days. Then give small volumes of grass for grazing increasing gradually. Grains and grazing in post harvest fields should be avoided.

DESCRIPTION:

The vaccine contains Toxoid & Bacterin of Clostridium perfringens Type ‘D’ adjuvanted with Aluminium Hydroxide Gel. This vaccine is used for providing prophylactiic protection against Enterotoxaemin disease in sheep & goats, which is caused by toxins of Clostridium perfringens Type ‘D’.

VACCINE SCHEDULE :

Before the start of disease season, vaccination with Enterotoxaemia vaccine should be done twice at 15 days intervals .
Pregnant animals should be vaccinated twice 15 days apart at least one month before delivery. This method confers protection to lambs up to 2 months age. All unvaccinated animals should be immediately vaccinated if the disease outbreak is noticed.

ADMINISTRATION :

Shake the vaccine well and inject 2.0 ml per animal subcutaneously in the neck region

PRESENTATION :

50 dose vial.

DURATION OF IMMUNITY :

In most animals, vaccination two times at 15 days interval results in protection for 9 months or more. Revaccination (once) after 9 months assures full protection for one year. In vaccinated animals also, the disease may strike, but it is very mild in nature.

STORAGE :

Vaccine should be stored at 2⁰-8⁰C in cold store/refrigerator protected from light.Do not freeze.

In: Sheep Vaccine Veterinary Products

7 Dec

Heamorrhagic Septicemia Black Quarter Vaccine,Inactivated I.P.

Formalin inactivated, Aluminium Hydroxide Gel Adjuvanted

This vaccine is a formalin-killed suspension of Pasturella multocida P-52 ≥ 109 CFU(H.S Component I.P.) and Clostridium chauvoei-49 ≥ 109(B.Q Component I.P.) bactrin adjuvanted with Aluminium hydroxide gel.

VACCINATION SCHEDULE :

The cattle should be vaccinated at least 15-20 days before the onset of seasonal outbreak. It requires about 14 days for the animal to develop full immunity. Immunity usually lasts for 10-12 months. Booster vaccination is required every year just before the seasonal outbreak.

ADMINISTRATION :

Shake well to make uniform suspension, inject 2 ml per animal subcutaneously in lower neck region. In calves of 2-8 months age, inject only 1 ml S/C per animal.

PRESENTATION :

25 dose vial.

STORAGE :

Store the vaccine at 2⁰-8⁰C.

In: Cattle Vaccine Veterinary Products

7 Dec

Black Quarter Vaccine I.P.

Aluminium Hydroxide Gel Adjuvanted

Black Quarter is a generalized infection of cattle caused by Clostridium chauvoei. It is characterized by emphysematous swelling of the muscles especially those of gluteal region. The incubation period is 1-5 days. The onset is sudden. The initial symptom is lameness with or without fever. Swellings at first are small, hot & painful. They may develop in the muscles of shoulder, hip, chest, back & flank. In a few hours, the swellings become extensive & crepitating.

The general symptoms are complete anorexia, marked prostration, muscular tremors, congested mucosa, dyspnoea, rapid pulse & high fever. The death occurs within 12-48 hours. On incision of affected swollen part infiltration with discoloured serum with gas is found. This gives typical sweetish-sour smell. The muscles are emphysematous, dark or black, friable giving a spongy character.

This vaccine is a suspension of formalin-killed Clostridium chauvoei culture(≥109) organisms per dose adjuvanted with Aluminium hydroxide gel.

VACCINATION SCHEDULE :

The cattle should be vaccinated at least 15-20 days before the onset of seasonal outbreak. It requires about 14 days for the animal to develop full immunity. Immunity usually lasts for 4-6 months. Booster vaccination is required every six month or just before the seasonal outbreak.

ADMINISTRATION :

Shake well to make uniform suspension, inject 2 ml per animal subcutaneously in lower neck region.

PRESENTATION :

50 dose vial.

STORAGE :

Store the vaccine at 2⁰-8⁰C.

In: Cattle Vaccine Veterinary Products

7 Dec

Heamorrhagic Septicemia Vaccine I.P.

Formalin Inactivated, Aluminium Hydroxide Gel Adjuvanted

Heamorrhagic Septicaemia commonly known as Gal-Ghotu in U.P. is an acute infectious disease of cattle, sheep, goat, pigs and deer. In India, the disease normally assumes endemic character just before and during the monsoon season. The onset of disease is sudden. A few animals die within 24-36 hours of sickness. The disease is characterized by high fever (1040- 1060 F), prostration, dropping ears, congested mucosa, lachrymation, fast pulse, rapid breathing with chills, Dyspnoea is marked by extended head, open mouth & protruded tongue. Bloody diarrhoea is common.

The oedematous form of disease is characterized by swellings above the eyes, flanks, in the region of pharynx, around the anus and vulva. It may extend from limbs to the body.

This vaccine is a suspension of formalin killed Pasteurella multocida. The vaccine is adjuvanted with Aluminium hydroxide gel (50 dose vial).

VACCINATION SCHEDULE :

The cattle should be vaccinated at least 15-20 days before the onset of seasonal outbreak. It requires about 14 days for the animal to develop full immunity. Immunity lasts for 4-6 months.

ADMINISTRATION :

Shake well to make uniform suspension, inject 2.0 ml per animal subcutaneously injection in lower neck region.

PRESENTATION :

50 dose vial.

STORAGE :

Store the vaccine at 2⁰-8⁰C.

In: Cattle Vaccine Veterinary Products

7 Dec

Ranikhet Disease-Avian Infectious Bronchitis Vaccine, Live, I.P.

Attenuated, Freeze Dried I.P.

Combivac RD + IB™ has been manufactured using ≥103.5 EID50 of Avian Infectious Bronchitis “Massachusetts strain” (H-120) virus and ≥ 106 EID50 of Ranikhet disease “LaSota strain” virus stabilized with Lactose 6% and gelatin 0.5% per dose. The vaccine confers protection against Ranikhet disease and Infectious Bronchitis disease.

VACCINATION SCHEDULE :

The vaccine is indicated in young healthy chicks (both broiler and layers) at the age of 4-7 days and repeated at 6-8 weelds and 16-18 weeks. It can be given to chicks at any age if there is prevalence of infectious Bronchitis or Rankihet disease in the area.

ADMINISTRATION :

Vaccine is reconstituted in diluent (4 ml, 20 ml and 40 ml for 100, 500 and 1000 dose vials respectively) or Sterile Normal Saline (0.9% Sodium Chloride). The vaccine can be given in drinking water. Remove drinkers & clean them. Keep chicks thirsty for One Hour. Pour enough clean water in drinkers which can be consumed in one-two hours. Add reconstituted vaccine in appropriate volumes. Add 5 gm of dry milk powder to one litre of water to stabilize vaccine. Add water to drinkers as normally done after 80% of vaccine water is used. Consult veterinary doctor for vaccination schedule etc.

PRESENTATION :

100, 500 and 1000 dose vials.

STORAGE :

Store in refrigerator (2⁰ to 8⁰C). Use within expiry date marked on label.

In: Poultry Vaccine Veterinary Products

7 Dec

Avian Infectious Bronchitis Vaccine, I.P. :

Live, Attenuated, Freeze Dried

The vaccine contains live, attenuated at least 103.5 EID50 of Avian Infectious Bronchitis “Massachusetts strain” H-120 per dose. The virus is stabilized and freeze dried. The vaccine confers protection against Infectious Bronchitis disease.

VACCINATION SCHEDULE :

The vaccine is indicated for broiler, layer chicks, adult layers and breeders for prevention of Infectious Bronchitis disease. Vaccinate at the age of 1-5 days and repeat at 3-4 weeks. Two doses are protective upto 6-8 weeks for Broilers. For Layers vaccinate again at 13-15 weeks age.

ADMINISTRATION :

Vaccine is reconstituted in diluent (4 ml, 20 ml and 40 ml for 100, 500 and 1000 dose vials respectively) or Sterile Normal Saline (0.9% Sodium Chloride). The vaccine can be given in drinking water. Remove drinkers & clean them. Keep chicks thirsty for One Hour. Pour enough clean water in drinkers which can be consumed in one-two hours. Add reconstituted vaccine in appropriate volumes. Add 5 gm of dry milk powder to one litre of water to stabilize vaccine. Add water to drinkers as normally done after 80% of vaccine water is used. Consult veterinary doctor for vaccination schedule etc.

PRESENTATION :

100, 500 and 1000 dose vial in freeze dried form.

STORAGE :

Store in refrigerator (2⁰ to 8⁰C). Use within expiry date marked on label.

In: Poultry Vaccine Veterinary Products

Rabies Veterinary Vaccine I.P., Inactivated, Cell Culture

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