Ranikhet Disease-Avian Infectious Bronchitis Vaccine, Live, I.P.

7 Dec

Ranikhet Disease-Avian Infectious Bronchitis Vaccine, Live, I.P.

Attenuated, Freeze Dried I.P.

Combivac RD + IB™ has been manufactured using ≥103.5 EID50 of Avian Infectious Bronchitis “Massachusetts strain” (H-120) virus and ≥ 106 EID50 of Ranikhet disease “LaSota strain” virus stabilized with Lactose 6% and gelatin 0.5% per dose. The vaccine confers protection against Ranikhet disease and Infectious Bronchitis disease.

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VACCINATION SCHEDULE :

The vaccine is indicated in young healthy chicks (both broiler and layers) at the age of 4-7 days and repeated at 6-8 weelds and 16-18 weeks. It can be given to chicks at any age if there is prevalence of infectious Bronchitis or Rankihet disease in the area.

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ADMINISTRATION :

Vaccine is reconstituted in diluent (4 ml, 20 ml and 40 ml for 100, 500 and 1000 dose vials respectively) or Sterile Normal Saline (0.9% Sodium Chloride). The vaccine can be given in drinking water. Remove drinkers & clean them. Keep chicks thirsty for One Hour. Pour enough clean water in drinkers which can be consumed in one-two hours. Add reconstituted vaccine in appropriate volumes. Add 5 gm of dry milk powder to one litre of water to stabilize vaccine. Add water to drinkers as normally done after 80% of vaccine water is used. Consult veterinary doctor for vaccination schedule etc.

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PRESENTATION :

100, 500 and 1000 dose vials.

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STORAGE : 

Store in refrigerator (20 to 80C). Use within expiry date marked on label.

7 Dec

Avian Infectious Bronchitis Vaccine, I.P. :

Live, Attenuated, Freeze Dried

The vaccine contains live, attenuated at least 103.5 EID50 of Avian Infectious Bronchitis “Massachusetts strain” H-120 per dose. The virus is stabilized and freeze dried. The vaccine confers protection against Infectious Bronchitis disease.

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VACCINATION SCHEDULE :

The vaccine is indicated for broiler, layer chicks, adult layers and breeders for prevention of Infectious Bronchitis disease. Vaccinate at the age of 1-5 days and repeat at 3-4 weeks. Two doses are protective upto 6-8 weeks for Broilers. For Layers vaccinate again at 13-15 weeks age.

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ADMINISTRATION :

Vaccine is reconstituted in diluent (4 ml, 20 ml and 40 ml for 100, 500 and 1000 dose vials respectively) or Sterile Normal Saline (0.9% Sodium Chloride). The vaccine can be given in drinking water. Remove drinkers & clean them. Keep chicks thirsty for One Hour. Pour enough clean water in drinkers which can be consumed in one-two hours. Add reconstituted vaccine in appropriate volumes. Add 5 gm of dry milk powder to one litre of water to stabilize vaccine. Add water to drinkers as normally done after 80% of vaccine water is used. Consult veterinary doctor for vaccination schedule etc.

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PRESENTATION :

100, 500 and 1000 dose vial in freeze dried form.

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STORAGE : 

Store in refrigerator (20 to 80C). Use within expiry date marked on label.

7 Dec

Fowl Pox Vaccine Live I.P.

Live, attenuated, freeze dried, ‘BM’ Strain

Fowl pox ‘BM’ strain vaccine has been developed with the use of latest techniques used in the vaccine research. This is the world’s best vaccine available today. It has been shown to be harmless and stress free even when given to one day old chicks and birds in lay. It offers solid immunity (95% protection) in vaccinated chicks under normal conditions. In areas prone to outbreak of fowl Pox disease two times vaccination (at 4-5 weeks and repeated at 14-15 weeks age) will in most cases completely assure protection against the disease.

This vaccine contains live, attenuated Fowl Pox ‘BM’ Strain virus propagate in chick embryo skin cell cultures. The vaccine contains ≥ 102TCID50 of virus per dose.

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VACCINATION SCHEDULE :

Primary : 4-5 weeks age.
Booster : 14-16 weeks age
• In case of outbreak revaccinate chicks immediately with this vaccine. In unvaccinated lots, vaccinate twice at 7 days intervals. Outbreaks can be controlled within 15 days of vaccination. .

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ADMINISTRATION :

Reconstitute 100 doses in 50 ml, 500 dose in 250 ml, 1000 doses in 500 ml diluent. Administer 0.5 ml intramuscularly into thigh region of chicks.

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PRESENTATION :

100, 1000 dose vial.

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STORAGE : 

Store the vaccine at 20– 80C. Cool the diluent on ice one hour before start of vaccination. Always keep the reconstituted vaccine on ice during vaccination and use it within 2 hours

7 Dec

Infectious Bursal Disease Vaccine, Inactivated (I.P.)

Aluminium Hydroxide Gel Adjuvanted

DESCRIPTION :

The vaccine contains inactivated intermediate strain virus of Gumboro Disease. It is adjuvanted with Aluminium hydroxide gel (2 mg Aluminium per dose ). Minimum titer per dose (before inactivation) is kept at >106.5 TCID50 of Gumboro Disease ‘Intermediate strain’ virus.

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VACCINATION SCHEDULE :

The vaccine is normally recommended for use in layers and breeders at the age of 16-17 weeks.

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ADMINISTRATION :

The vaccine should be given as subcutaneous injection in the lower neck area. The dose is 0.5 ml per bird.

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PRESENTATION :

1000 dose pack

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STORAGE : 

Store the vaccine at 20– 80C.

7 Dec

Ranikhet Disease Vaccine Live, Lentogenic ‘LaSota’ strain, I.P.

Attenuated, freeze dried

DESCRIPTION :

Ranikhet disease LaSota Strain is a Lentogenic strain. It is slightly more invassive than ‘F’ Strain. It is quite safe to 1-7 days old tender chicks including layers. It confers quite good immunity lasting for about 6 weeks.
The vaccine contains ≥ 106 EID50 units of Ranikhet disease LaSota Strain virus per dose propogated in SPF eggs.

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VACCINATION SCHEDULE :

Primary : Chicks should be vaccinated at 1-3 weeks age.
Booster : As per advice of doctor.

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ADMINISTRATION :

Reconstitute 200 doses in 8 ml, 500 doses in 20 ml, 1000 doses in 40 ml, 2000 doses in 80 ml and 5000 doses in 200 ml diluent. Give 1 drop orally or in nostril or in eye or by drinking water method ( as in case of F strain ).

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PRESENTATION :

200, 500, 1000, 2000 and 5000 dose vials.

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STORAGE : 

Store the vaccine at 20– 80C. Cool the diluent in ice one hour before start of vaccination. Always keep the reconstituted vaccine on ice during vaccination and use it within 2 hours.

6 Dec

Infectious Bursal Disease Vaccine Live I.P.(Intermediate Plus)

Gumboro Disease is an actue highly contagious disease of young chicks (2-6 weeks old). It also affects chicks of 7-10 weeks in mild manner. Older birds do not develop clinical disease.
The disease is associated with serve damage to Bursa in Fabricius in young chicks. This leads to defective immune systems, making chicks susceptible to many disease including disease like Ranikhet Disease inspite of Vaccination.
The disease spreads by contaminated feed, water and air. The incubation period is short (2-3 days). The affected chicks become dull, depressed, go off feed, have ruffled feathers and huddle in corners. Soon diarrhea develops leading to progressive weakness & death in 5-6 days. It can affect 80% of the flock but kills about 2-10% chicks only.
On postmortem, bursa is enlarged, oedamatous and yellowish. At times bursa show petechial or ecchymotic haemorrhages on mucosal surface. Occasionally, extensive haemorrhages through the entire bursa are observed. Pinpoint haemorrhages can be seen in muscles of breast, thighs and legs. Spleen is enlarged caecal tonsil and thymus are hyperemic.

DESCRIPTION :

The vaccine contains live, low passage Gumboro Disease Intermediate plus strain virus propagated in SPF chicken embryo fibroblast cell culture. The vaccine virus(serotype 1) successfully immunizes the chicks with maternal antibodies yet is nearly It is available in freeze dried form. The vaccine contains atleast ≥102 TCID50 of virus per dose. The vaccine is available in 100, 200, 500 and 1000 dose vial.

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METHOD OF VACCINATION :

  1. Use 4 ml diluent for 100 dose, 8 ml for 200 dose, 20 ml for 500 dose and 40 ml for 1000 dose vial of Gumboro vaccine.
  2. Remove 1 ml vaccine diluent with a syringe and needle from the diluent vial & reconstitute the vaccine.
  3. Remove reconstituted vaccine and mix with remaining diluent.
  4. The vaccine can also be given in cold non-sanitized drinking water stabilized with 2 gm skimmed milk powder per liter of water. Use enough water(for 1000 chicks use one litre per day of age e.g. for 10 days old chicks 10-litre water) that the chicks can drink in 1 to 2 hours. After mixing the required number of vaccine doses throughly in the water, the vaccine water is offered to the chicks in clean waterers. The chicks are kept thirsty for 2-3 hours before offering vaccine water. Vaccination should preferably be done during motning hours.
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VACCINATION PROGRAMME

Chicks should be vaccinated at 10-12 days of age and repeated at 4 weeks of age oral route.

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STORAGE : 

Vaccine should be stored at 20– 80C, in refrigerator. Vaccine diluent can be stored at room temperature in cool area.

6 Dec

Infectious Bursal Disease Vaccine  Live (I.P.)

Live, attenuated, freeze-dried, ‘Intermediate’ Strain.

DESCRIPTION :

INFECTIOUS BURSAL DISEASE VACCINE, I.P. :
Live, attenuated, freeze-dried, ‘Intermediate’ Strain.
DESCRIPTION :
The vaccine contains live, low passage Gumboro disease (Intermediate) strain virus propagated in SPF chicken embryo fibroblast cell culture and is available in freeze dried form. The vaccine contains≥102 TCID50 virus per dose.

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VACCINATION SCHEDULE :

Vaccinate at 12-14 days age and repeat at 4 weeks age.

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ADMINISTRATION :

Reconstitute 100 doses in 4 ml, 200 doses in 8 ml, 500 doses in 20 ml and 1000 doses in 40 ml, vaccine diluent . Give one drop orally or in nostril or in eye.

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PRESENTATION :

100, 200, 500 and 1000 dose vials.

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STORAGE : 

Store the vaccine at 20– 80 C. Vaccine diluent can be stored at room temperature in cool area.

6 Dec

Ranikhet Disease Vaccine Inactivated I.P.

Aluminium Hydroxide Gel Adjuvanted

DESCRIPTION :

Ranikhet Disease Vaccine Inactivated / Killed is prepared by treating Ranikhet ‘LaSota’ strain virus with formalin & stabilized. It is adjuvanted with aluminium hydroxide gel (2 mg Aluminium per dose), minimum titer per dose (before inactivation) is kept at >108.6 EID50 of Ranikhet Disease LaSota strain virus.

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VACCINATION SCHEDULE :

The vaccine is normally recommended for use in layers and breeders at the age of 16-17 weeks.

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ADMINISTRATION :

The vaccine should be given intramuscularly in thigh region. The dose is 0.5 ml per bird. Younger chicks (4-5 days old) suffering from respiratory disease can be vaccinated with 0.25 ml/chick.

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PRESENTATION :

1000 doses

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STORAGE : 

Store the vaccine at 20– 80C.

6 Dec

Ranikhet Disease Vaccine, Live Lentogenic ‘LaSota’ Strain I.P. SUPER LaSotaTM

Super LaSotaTM Vaccine is the latest contribution of Bio-Med to the bandbagon of currently existing Ranikhet disease vaccines. Its uniqueness lies in its characteristics of being highly immunogenic although being stress free. Hence it shall protect (broiler / layer) chicks (young chicks or birds in lay) against the potential attack of very-very virulent Ranikhet disease virus.
Super LaSotaTM has been developed in DSIR (Govt. of India) certified lab of Bio-Med by extensive research using CLONING & SELECTION procedure. Super LaSota’s I.C.P Index is 0.0125 & C.E.P Index is 115.5 hours. It causes insignificant pathogenic changes in the lung & airsacs of young chicks. The chicks vaccinated with this vaccine, resisted challenge by infectious Ranikhet disease virus(90% Survival in comparision with about 10% conferred with regular Lasota/F/B-1 Strain vaccines in a trial). All these characteristics makes Super LaSotaTM a distinct clone of R.D. virus.

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PRESENTATION :

This vaccine is available in Freeze Dried from in 1000 and 5000 dose pack, Each dose of vaccine contains ≥ 106 EID50 per dose.

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RECOMMENDATION :

Vaccinate Chicks (Boiler/Layer) at 1-7 days, Repeat at 20-28 days. For Layers, it can be given in drinking water to birds.

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METHOD OF ADMINISTRATION :

The vaccine is to be reconstituted in normal saline(0.9% Sodium Chloride Solution). Use 40 ml and 200 ml diluent for reconstitution of 1000 dose and 5000 dose vial respectively.
Administer ‘one’ drop by dropper in the mouth of each chick. Alternatively, the recontituted vaccine can be given in drinking water also. Allow birds to be thirsty for 1/2 hour to one hour depending on climate. Remove drinking & clean them. Use fresh water only. Do not use medicated or water with chlorine or any disinfectant. Add vaccine, proportionately in drinkers with enough water that should be consumed within one or two hours. Dry milk powder can be added (100gm per 20 litre) to drinking water for stabilizing vaccine.

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STORAGE : 

The vaccine must be stored in refrigerator(20 -80C) until its use.

6 Dec

Ranikhet Disease Vaccine, Live, Lentogenic ‘F’ strain, I.P. :

Live, Attenuated, Freeze Dried

DESCRIPTION :

Ranikhet disease ‘F’ Strain is a lentogenic Strain. It is least stress causing vaccine virus strain in this class. It can be used at any age including birds in lay without any effect on laying as booster vaccine. The vaccine contains live attenuated Ranikhet disease ‘F’ strain virus propagated in SPF chicken eggs and is available in freeze dried form. The vaccine contains ≥ 106 EID50 virus per dose.

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VACCINATION SCHEDULE :

Primary :
. 1-7 days old chicks.
. This vaccine can be given in cold drinking water for mass vaccination to provide booster immunity.

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ADMINISTRATION :

Reconstitute 100 doses in 4 ml, 200 doses in 8 ml, 500 doses in 20 ml, 1000 doses in 40 ml, and 2000 doses in 80 ml using ice cooled vaccine diluents.
(a) Oral or I/ Nasal, I/Ocular method. Vaccinate chicks by putting one drop in the month of the chick or by one drop in eye or in one nose.
(b) By drinking water methods- The reconstituted vaccine is mixed in cold drinking water. Use enough water (for 1000 chicks use one litre water stabilized with 2 gm dry baby milk powder per day of age) which the chicks can drink in 1 to 2 hours.

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PRESENTATION :

100, 200, 500, 1000 and 2000 dose vials.

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STORAGE : 

Store the vaccine at 20– 80C. Cool the diluent in ice one hour before start of vaccination. Always keep the reconstituted vaccine on ice during vaccination and use it within 2 hours.

Company information

Bio-Med (P) Limited was established with an abiding faith in the wisdom enshrined in the age-old saying………….
“Prevention is better than cure”
It was with this objective that Bio-Med embarked on its noble mission of producing world-class vaccines essential to the needs of a developing country-India.